She is Sheldon's favorite of all his living family members, as he shows her no resentment at all, unlike his resentment toward his other family members, except his mother. She was widowed in when her husband, Sheldon's grandfather " Pop-Pop ", passed away. She had only been mentioned and had not appeared in the series, until " The Meemaw Materialization " during which she made her first appearance, in February She is played by Academy Award nominee June Squibb.
In Young Sheldon , she is portrayed by actress Annie Potts. Like Sheldon has explained, Meemaw is a wonderful, warm, loving, sweet and wise grandmother who's protective and caring for Sheldon. She calls him "Moon-pie" because he's so "nummy-nummy, she could just eat him up! Meemaw is a primary character on Young Sheldon. She occasionally helped her daughter Mary look after the latter's children Sheldon, Missy and Georgie but when Mary offered to take a job at the church, Meemaw declined to take care of her grandchildren full-time perhaps because she's gotten old and lacks the energy to do so.
Pilot Young Sheldon. Meemaw was considered by her children and grandchildren to be an excellent cook, especially when she made her homemade brisket. George Sr. She's the only one to comfort Sheldon after Stephanie Hanson's death, which is part of the reason Sheldon regards her so fondly.
She is introduced in Young Sheldon as a caring grandma. Poker, Faith, and Eggs. When George gets a heart attack, She finds out George had been taken the emergency room at the hospital, so she had to watch the grand kids. The trio, however, stole Meemaw's car while she was sleeping and with Georgie driving, they had hit a few trash cans but they made it to the hospital at roughly the same time as her, and Meemaw plays it cool in front of Mary when asked why the kids are there.
Meemaw tries to date both John Sturgis and Ira, but is convinced by Sheldon to set ground rules. She thinks he is trying to interfere with her relationships; he offers to draw up a friendship agreement.
