Bariatric surgery and other therapeutic options for obese patients are often evaluated by the loss of weight, reduction of comorbidities or improved quality of life.
However, little is currently known about potential therapy-related changes in the adipose tissue of obese patients. The aim of this study was therefore to quantify fat fraction FF and T1 relaxation time by magnetic resonance imaging MRI after Roux-en-Y gastric bypass surgery and compare the resulting values with the preoperative ones. Corresponding MRI data were available from 23 patients 16 females and 7 males that had undergone MRI before M0 and one month after M1 bariatric surgery.
Patients were 22β59 years old mean age Average BMI values were Average relaxation times T1 VAT were Corresponding T1 SAT times were In conclusion, bariatric surgery is apparently not only related to a significant reduction in common parameters of adipose tissue distribution, here BMI and total visceral fat volume, but also significant changes in T1 relaxation time and fat fraction of visceral adipose tissue.
Such quantitative MRI measures may potentially serve as independent biomarkers for longitudinal and cross-sectional measurements in obese patients. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Basic data is now provided, see table attached. We hope this will be sufficient to grant evaluation of statistical measures. This ongoing prospective clinical trial is based on a study protocol that prohibits prior publication of further data, especially when directly linked to the primary end points. The trial shall be finished in June In accordance with the IRB contact details attached below we therefore cannot provide additional data at this moment of time.
